Residual solvent testing with an electronic nose

Pharmaceutical products can contain residual traces of the solvents that are used in the manufacture of drugs. The residual solvents are not completely removed by practical manufacturing techniques. Their content in pharmaceutical products should be evaluated and drug products should contain no higher levels of residual solvents than those recommended by health authorities, like the FDA. The Alpha MOS Fast Dual Gas Chromatograph Electronic Nose can be used for rapid residual solvent testing. The analysis offers a good separation of the compounds in less than 2 minutes. The system also shows a sensitivity which allows detecting concentrations as low as the thresholds defined by international regulations.