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Method for extraction of tricyclic antidepressants from whole blood using ISOLUTE HCX columns and RapidTrace
Cocaine is absorbed and metabolized extremely efficiently and rapidly through the liver which makes it difficult to detect in drugs of abuse testing. When screening for the presence of cocaine in urine it is more appropriate to test for the presence of the major metabolite of cocaine; benzoylecgonine.

Method for the extraction of cyclosporine from whole blood using ISOLUTE SI columns and RapidTrace
workstation
Cyclosporine is an immunosuppressant drug most significantly used in post-operative organ transplants to reduce the chance of rejection of donor organs by decreasing the activity of the patient’s immune system. Subsequent to an organ transplant, patients are tested at regular intervals for the presence of very low levels of the compound.

Extraction of Ethyl Glucuronide (EtG) from urine using EVOLUTE AX and RapidTrace+ workstation
This application note has been optimized on the RapidTrace+; an updated version of the current RapidTrace software which allows the system to process smaller bed heights than were previously possible. The application note shows analyte recoveries all above 97% with RSDs >10%.

Extraction of pain management drugs from urine using EVOLUTE CX with the RapidTrace + automated SPE workstation prior to LC-MS-MS
This application note describes the extraction of 21 different drugs in urine which are typically screened for pain management panels using EVOLUTE CX 100 mg/3 mL cartridges and automated using the RapidTrace workstation.

Automated SPE of tricyclic antidepressant drugs from serum
This application note shows the automated process of extracting tricyclic antidepressant drugs from serum using the RapidTrace SPE workstation.