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Extraction of barbiturates from oral fluid using ISOLUTE SLE+ after collection with the Oral-Eze collection device prior to GC/MS analysis
This application note describes the extraction of butalbarbital, butabarbital, amobarbital, pentobarbital, secobarbital, hexobarbital and phenobarbital from oral fluid matrix collected using the Oral-Eze collection devices.

Extraction of amphetamines and metabolites from urine using ISOLUTE SLE+ prior to GC/MS analysis
Prior to extraction, a simple oxidation step is performed to eliminate sympathomimetic compounds such as ephedrine and pseudoephedrine so they do not interfere with quantitation of methamphetamine.

Extraction of a drugs of abuse panel from oral fluid using ISOLUTE SLE+ after collection with the Oral-Eze collection device prior to UPLC-MS/MS analysis
An effective and efficient ISOLUTE SLE+ protocol optimized for both 400 uL and 1 mL sample capacity column formats is described in this application note.

Extraction of 11-nor-9-carboxy-tetrahydrocannabinol from hydrolyzed urine by ISOLUTE  SLE+ prior to GC/MS analysis
The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 87% with RSDs lower than 10% for all analytes, and is optimized for use with 1 mL sample capacity ISOLUTE SLE+ columns.

Extraction of barbiturates from whole blood using ISOLUTE SLE+ prior to GC/MS analysis
ISOLUTE SLE+ columns with 1 mL sample capacity are used to extract whole blood samples following a straightforward sample dilution. No protein precipitation or other pre-treatment is required prior to sample loading.