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Extraction of a range of amphetamines and metabolites from human urine using ISOLUTE SLE+ columns prior to GC-MS analysis
The methodology in this application has been designed to give an effective and efficient supported liquid extraction protocol for the clean-up and concentration of a range of forensically significant amphetamines followed by derivatization to optimize for GC-MS analysis.

Extraction of cocaine and metabolites from hydrolyzed urine using ISOLUTE SLE+ prior to GC-MS analysis
An effective and efficient ISOLUTE SLE+ protocols optimized for sample loading volumes of either 400 uL or 1 mL are described in this application note.

Extraction of 45 multi class drugs of abuse from hydrolyzed urine using ISOLUTE SLE+ prior to LC-MS/MS analysis
The method described in this application note achieves high reproducible recoveries for a wide range of drugs of abuse and metabolites from hydrolyzed urine.

Extraction of 45 multi class drugs of abuse from urine (non-hydrolyzed) using ISOLUTE SLE+ prior to LC-MS/MS analysis
The method described in this application achieves high reproducible recoveries for a wide range of drugs of abuse and metabolites from non-hydrolyzed urine.

Extraction of synthetic cannabinoids (SPICE) from whole blood using ISOLUTE SLE+ prior to GC-MS analysis
This application note shows an effective and efficient ISOLUTE SLE+ protocol has been developed that is optimized for extraction of 800 uL of pre-treated matrix.

Extraction of bath salts from human urine using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note to extract baths salts from urine ranged from 87-99% with RSDs below 10% for all analytes.

Extraction of cortisol from human urine using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note ranged from 99-101% with RSDs below 5% for all analyes.

Extraction of cortisol from human saliva using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note ranged from 96-99% with RSDs below 3% (n=7) for all analyes.

Extraction of synthetic cannabinoids (SPICE) from oral fluid using ISOLUTE SLE+ prior to GC-MS analysis
This application note describes the extraction of a range of synthetic cannabinoids and metabolites from oral fluid collected using the Quantisal oral fluid collection device prior to GC-MS analysis.

Extraction of synthetic cannabinoids from hydrolyzed urine using ISOLUTE SLE+ prior to GC-MS analysis
Effective and efficient ISOLUTE SLE+ protocols optimized for sample loading volumes of either 400 uL or 1 mL are described in this application note.

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