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Protein and phospholipid removal products
ISOLUTE PLD+ protein and phospholipid removal plates and columns provide a very effective but extremely simple sample clean-up for LC-MS/MS analysis.

ISOLUTE PLD+ protein and phospholipid removal products – questions and answers
Here you can find useful information on the Biotage ISOLUTE PLD+ in the form of a Q&A.

How to use ISOLUTE PLD+ protein and phospholipid depletion plates
ISOLUTE PLD+ plates provide extremely efficient removal of proteins and phospholipids from blood based samples using a simple 3 step procedure.

How to use ISOLUTE PLD+ protein and phospholipid depletion columns
ISOLUTE PLD+ columns provide extremely efficient removal of proteins and phospholipids from blood based samples using a simple 3 step procedure.

Evaluation of a novel 96-well filter plate for the effective removal of serum proteins and phospholipids prior to LC-MS/MS analysis
This poster evaluates the performance of a novel 96-well filter plate for the simultaneous removal of proteins and phospholipids prior to LC-MS/MS analysis.

Evaluation of 25-hydroxy vitamin D extraction using phospholipid depletion plate technology and method comparison using automated sample preparation
This poster demonstrates the use of a novel protein and phospholipid depletion plate, for the extraction of 25-hydroxy vitamin D. The extraction protocol was ultimately transferred to an SPE automation platform and method performance versus manual processing was compared.

Comparison of sample preparation strategies for the extraction of methylmalonic acid prior to LC-MS/MS analysis
A range of techniques of varying complexity were evaluated: protein precipitation, phospholipid depletion, supported liquid extraction and solid phase extraction using both silica and polymer-based mixed-mode anion exchange chemistries. Method performance was evaluated for evaporative effects, assay recovery, ion suppression and phospholipid removal.

Extraction of a range of acidic, basic and neutral drugs from plasma using ISOLUTE PLD+ plates prior to LC-MS/MS analysis
This application note describes the use of the ISOLUTE PLD+ protein and phospholipid removal plate for clean-up of a range of acidic, basic and neutral drugs from plasma.

Biotage RapidTrace+ user manual
This is a general guide for Biotage's RapidTrace+ automated SPE workstation. It will explain how to install, start and use the system. It also contains other useful information like safety instructions.

An automated dual stage SPE procedure for 15 F2t-isoprostane (8-iso prostaglandin2a) from BSA as lipid markers of oxidative stress
In this work, the automation of an exisiting SPE procedure was implemented. A dual stage cleanup strategy was employed.

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